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Vol. 9, Issue 3 (2020)

Anti-inflammatory effects of Lablab purpureus Linn in polyphenolic fraction from methanolic leaf extract on experimental animal model

Author(s):
C Pramod, Dr. Sudhakaran Nair, Dr. Jyoti Harindran and Dr. Ratheesh
Abstract:
Natural products have been a source of leads for the development of the most effective drugs currently available for the treatment of a variety of human diseases. Biodiversity will continue to provide novel leads for drug development, but major obstacles like, the large-scale procurement of sufficient source material for bulk production, the potency and inherent toxicity of many natural products resulting in narrow therapeutic indices, as well as significant problems associated with the development of suitable vehicles and dosing schedules for the administration of the drugs to patients limit efficient progress and result in decreased interest in the pharmaceutical sector. Demand for medicinal plant is increasing in both developed and developing countries. An abundance of ethnomedical information on plant uses can be found in scientific literature but has not yet been compiled into a usable form. Collection of ethnomedical information especially in the developing countries remains primarily an academic endeavour of little interest to most industrial groups. Allergy and inflammation are the one of the immune dysfunctions, which is a serious health problem worldwide. Substances that cause allergy are called allergens, such as pollen, food, dust mites, cosmetics, mould spores and animal hairs. Inflammation may due to the release of mediators during ejection of these allergens. A large number of phytochemicals from the diet have been demonstrated to exhibit antiinflammatory activities by interfering with multiple signalling pathways. The polyphenolic fraction of the methanolic extract of Lablab purpureus Linn was subjected to various antiinflammatory studies (Chronic). We proved that it have promising antiinflammatory (>0.005) activities when compared to the control.
Pages: 338-344  |  497 Views  118 Downloads


The Pharma Innovation Journal
How to cite this article:
C Pramod, Dr. Sudhakaran Nair, Dr. Jyoti Harindran, Dr. Ratheesh. Anti-inflammatory effects of Lablab purpureus Linn in polyphenolic fraction from methanolic leaf extract on experimental animal model. Pharma Innovation 2020;9(3):338-344.

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