Non-invasive transitional cell carcinoma in a Labrador
M Thangapandiyan, P Krishnaveni, V Kumar and GV Sudhakar Rao
A 12-year-old, female Labrador was presented to the Madras Veterinary College Teaching Hospital with the history of pollakiuria and hematuria. On Ultrasound scanning, echogenic area noticed in the lumen of the urinary bladder adherent to the bladder wall. Cytological examination of the urine sample was suggestive of transitional cell carcinoma. Partial cystectomy was performed and the tumor was sent to the Department of Veterinary Pathology for histopathological examination and confirmatory diagnosis. On microscopical examination of the papillary projections found to be protruding from the mucosa with a central fibrovascular core. The basement membrane was intact without any tumor invasiveness into submucosal layer. Immunohistochemical staining was done with monoclonal antibodies against cytokeratin which is normally found in urothelium. It was found to be intensely positive. Based on Cytology, Histopathology and Immunohistochemistry it was confirmed as a non-invasive transitional cell carcinoma.
How to cite this article:
M Thangapandiyan, P Krishnaveni, V Kumar, GV Sudhakar Rao. Non-invasive transitional cell carcinoma in a Labrador. Pharma Innovation 2020;9(3):38-39.