Vol. 9, Issue 10 (2020)

Author(s):
Boniface Josephus, Hassan Braimah Yesufu and Fatimah A Goje

Abstract:
In this study, the antimicrobial evaluation of alpha Amyrin obtained from the stem bark of ficus sycomorus was reported. Standard method was adopted for the screening of phyto-chemicals, while a combination of column and preparative thin layer chromatography lead to the compound (F_A) a light yellow crystal. The compound F_A showed significant inhibition on the tested organisms, E.coli (IC₅₀ = 0.81) S. typhi (IC₅₀= 0.84) S. aureus (IC₅₀= 0.66) K. Pneumonia (IC₅₀= 0.06) and was identified based on spectra evidence to contain a mixture of α-amyrin acetate.