Antimicrobial evaluation of Amyrin acetate from the stem bark of Ficus sycomorus (Moraceae)
Author(s): Boniface Josephus, Hassan Braimah Yesufu and Fatimah A Goje
Abstract: In this study, the antimicrobial evaluation of alpha Amyrin obtained from the stem bark of ficus sycomorus was reported. Standard method was adopted for the screening of phyto-chemicals, while a combination of column and preparative thin layer chromatography lead to the compound (FA) a light yellow crystal. The compound FA showed significant inhibition on the tested organisms, E.coli (IC50 = 0.81) S. typhi (IC50= 0.84) S. aureus (IC50= 0.66) K. Pneumonia (IC50= 0.06) and was identified based on spectra evidence to contain a mixture of α-amyrin acetate.