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Vol. 8, Issue 9 (2019)

A prospective study on prescription pattern of proton pump inhibitors in gastrointestinal disorders

Author(s):
K Sampath Reddy, G Ravi Varma, P Narsimha Reddy, D Sudheer Kumar and P Kishore
Abstract:
Background: Proton pump inhibitors (PPIs) are widely prescribed classes of medications that are used in the treatment of multiple gastrointestinal (GI) disorders like upper Gastro intestinal disorders, including Gastro-Esophageal Reflux Disease (GERD), Dyspepsia, Peptic Ulcer Disease (PUD), Non-Steroidal Anti Inflammatory Drugs(NSAIDs)-induced ulcer, eradication of Helicobacter pylori (H. pylori) infections.
Methodology: A Prospective observational study was conducted in 190 patients. Pertinent information was collected from patients and prescribing pattern of PPIs was analyzed among the gastrointestinal disorders.
Results: Of 190 patients with gastrointestinal disorders, male patients were 59% and these disorders were observed more in the age group of 41-50 years (26%). Among 190 patients, the most commonly observed gastrointestinal disorders were gastric ulcer (29%) followed by gastritis (23%). In this study, PPIs were frequently prescribed as monotherapy (84%) and the most commonly prescribed PPI was pantoprazole (48%) followed by rabeprazole (34%) and esomeprazole (18%). In H. pyloric infections most commonly used H. pyloric kits were esomeprazole kit (54%) followed by pantoprazole kit (46%).
Conclusion: We observed that the most commonly observed gastric disorders were gastric ulcer and gastritis and the most commonly prescribed PPIs were patoprazole followed by rabeprazole. H.pyrolic infection was treated more with esomeprazole kits. The usage of pantoprazole was more as it was the most preferred drug in the majority of the gastric disorders observed and also it is one of the recommended drugs by NLEM.
Pages: 237-240  |  747 Views  183 Downloads


The Pharma Innovation Journal
How to cite this article:
K Sampath Reddy, G Ravi Varma, P Narsimha Reddy, D Sudheer Kumar, P Kishore. A prospective study on prescription pattern of proton pump inhibitors in gastrointestinal disorders. Pharma Innovation 2019;8(9):237-240.

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