Toll Free Helpline (India): 1800 1234 070

Rest of World: +91-9810852116

Free Publication Certificate

Vol. 8, Issue 8 (2019)

Moderate to severe anthelmintic resistance against commonly used anthelmintics in a village goat flock of Haryana

Author(s):
Priyanka, Sukhdeep Vohra, Satyavir Singh and Arun K Sangwan
Abstract:
The present study was conducted to detect the status of anthelmintic resistance of commonly used anthelmintic drugs against gastrointestinal nematodes in goats of village Satnali, district Mahendergarh, Haryana. Sixty goats with eggs per gram of more than or equal to 150 were divided into four groups i.e. G1, G2, G3 and G4 of 15 animals each. Group G1, G2 and G3 were treated with fenbendazole @ 10 mg/kg b.wt. orally, morantel @ 20 mg/ kg b.wt. orally and ivermectin @ 0.4 mg/kg b.wt. subcutaneously, respectively. Group G4 served as untreated control. Faecal egg counts of goats were ascertained on day of treatment (0 day) and 12th day post treatment (PT) of all groups by the modified McMaster technique. Pooled faecal cultures were made to recover infective larvae on day 0 and 12 PT. Results revealed that fenbendazole reduced the faecal egg counts by 14.23% with upper and lower confidence levels as 39.10% and 20.29%, respectively indicating severe anthelmintic resistance. Morantel and ivermectin reduced the faecal egg counts by 60.87% and 89.72%, respectively on 12th day PT with upper and lower confidence levels as 83.20% and 8.86% and 97.11% and 63.51%, respectively indicating moderate anthelmintic resistance against both drugs. The post-treatment coproculture showed larvae of Haemonchus contortus and Strongyloides sp. Thus, the present study revealed presence of multiple anthelmintic resistance of fenbendazole, morantel and ivermectin against H. contortus in goats of unorganized sector in Mahendergarh, Haryana.
Pages: 213-216  |  520 Views  43 Downloads


The Pharma Innovation Journal
How to cite this article:
Priyanka, Sukhdeep Vohra, Satyavir Singh, Arun K Sangwan. Moderate to severe anthelmintic resistance against commonly used anthelmintics in a village goat flock of Haryana. Pharma Innovation 2019;8(8):213-216.

Call for book chapter