Toll Free Helpline (India): 1800 1234 070

Rest of World: +91-9810852116

Free Publication Certificate

Vol. 8, Issue 7 (2019)

Intraoperative apparatus-based blood reinfusion in the aspect of oncological safety in patients with renal cell carcinoma complicated with tumor venous thrombosis

Author(s):
Yuliya Mota, Ihor Kobza, Svitlana Lebedeva and Volodymyr Vovk
Abstract:
Aim: Determine the role of intraoperative apparatus-based blood reinfusion in the aspect of oncological safety in patients with renal cell carcinoma, complicated with tumor venous thrombosis.
Material and Methods: The results of cytological examination of tumor contamination of blood sediment material from the surgical field during the cavatomy and washed erythrocytes after processing with the use of «Medtronic Autolog» device were analyzed in 8 patients with renal cell carcinoma, complicated with tumor thrombosis of the inferior vena cava, who were hospitalized to the Vascular surgery department of Lviv Regional Clinical Hospital for the period from 2017 to 2019: 6 (75.0%) men, 2 (25.0%) women, median of age 59.5 (49-72) years. The blood sent for research was centrifuged. From the sediment material the smears were prepared, stained with hematoxylin-eosin and examined through the Nikon E200 optical microscope with Nikon D5000 camera.
Results and Discussion: At radical nephrectomy with thrombectomy from the inferior vena cava a cytological examination of the blood sediment material from the operative field during the cavatomy revealed the presence of peripheral blood elements, among which in 4 cases it was possible to visualize the tumor cells. Also in 5 cases an accumulation of neutrophilic leukocytes, single lymphocytes was revealed. The results of cytological examination of sediment material of washed red blood cells after processing with «Medtronic Autolog» device in all 8 cases have revealed the presence of only erythrocytes. Thus, the obtained results suggest that intraoperative reinfusion of washed red blood cells using the «Medtronic Autolog» device may provide the necessary ablastics by preventing tumor cells and leukocytes from entering the patient’s bloodstream.
Conclusions: Intraoperative reinfusion of washed erythrocytes in patients with renal cell carcinoma, complicated with tumor venous thrombosis, during radical nephrectomy and thrombectomy from the inferior vena cava can significantly reduce the need for donor blood in compliance with the requirements of ablastics.
Pages: 311-313  |  347 Views  35 Downloads


The Pharma Innovation Journal
How to cite this article:
Yuliya Mota, Ihor Kobza, Svitlana Lebedeva, Volodymyr Vovk. Intraoperative apparatus-based blood reinfusion in the aspect of oncological safety in patients with renal cell carcinoma complicated with tumor venous thrombosis. Pharma Innovation 2019;8(7):311-313.

Call for book chapter