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Vol. 8, Issue 7 (2019)

Probiotic and anticancer activity of fermented rice water

Thilagavathi P, Rekha A and Soundhari C
Objective: Cancer is a major health concern and it remains one of the main causes of death among human being. Free radicals are known to be the influencing factors for many diseases. The excessive free radical production and low antioxidant defense is caused by oxidative stress, which is harmful and also strongly associated with cancer development. Consuming overnight fermented rice water is a very old practice followed in Tamil Nadu, India. The present study was attempted to investigate the health benefits of Fermented rice water.
Methods: The cooked fermented white rice water (0 hour, 24 hours) samples were used in the study. Isolation, identification of organism was done by morphological tests like gram staining, motility, endospore staining and catalase. The antibacterial activities were performed using agar disc diffusion method against Escherichia coli, Salmonella typhi, Staphylococcus aureus, Klebsiella punemoniae. Phenolic compounds were separated using chloroform solvent from fermented white rice water. The separated fractions were used for further studies, and their total phenolic content was determined by qualitative and quantitative methods. The compounds present in the (0 and 24 hours) samples were further analyzed using GC-MS assay.
Results: 0 hour fermented cooked rice water contained ten compounds whereas 24 hours fermented rice water contained twenty three compounds. The fermented cooked rice water was capable of inhibiting proliferation of hepato cellular carcinoma cells with IC50 of 125 µg/ml inhibiting 49.41% of liver cancer cells.
Conclusion: The study reports the fermented cooked rice water as natural therapeutic agents with antimicrobial, antioxidant and anticancer activities. Daily intake of this fermented rice water in our diet is beneficial in many ways and would be a natural source of phenolics for common man in developing countries.
Pages: 290-295  |  4576 Views  2014 Downloads

The Pharma Innovation Journal
How to cite this article:
Thilagavathi P, Rekha A, Soundhari C. Probiotic and anticancer activity of fermented rice water. Pharma Innovation 2019;8(7):290-295.

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