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Vol. 8, Issue 7 (2019)

Study of the sapropel extract influence on the main biochemical and hematological blood indices of rats

Author(s):
Strus Oksana and Polovko Nataliia
Abstract:
Humic substances are a specific group of macromolecular compounds formed in peat and sapropels in the process of decomposition of dead plant and animal tissues. It was set out that products based on humic substances possess a wide range of biological properties that are already widely used in veterinary medicine and medicine. In particular, preparations containing humic substances affect the nonspecific and specific resistance of the organism, have antioxidant, anti-inflammatory, antiviral, antibacterial, antifungal, membrane and hepatoprotective properties, the ability to exacerbate the activity of metabolic processes in the body. The sapropel extract was obtained from Prybych deposit, located in Volyn region, Ukraine. The technology of sapropel extract production using the cavitation method provides better extraction of humic and fulvic acids, since their content exceeds 20%. The objective of our work was to determine the effect of sapropel extract on the basic biochemical and hematological blood indices of clinically healthy rats during oral administration over 30 days. According to the results of the study, the absence of chronic toxic effects of sapropel extract on the basic biochemical and hematological indices in rats blood was established.
Pages: 47-52  |  741 Views  71 Downloads


The Pharma Innovation Journal
How to cite this article:
Strus Oksana, Polovko Nataliia. Study of the sapropel extract influence on the main biochemical and hematological blood indices of rats. Pharma Innovation 2019;8(7):47-52.

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