Vol. 8, Issue 6 (2019)

Author(s):
Sandeep Kumar, Ranbir Singh Bisla, Prem Singh, R N Chaudhary, Babu Lal Jangir and Ram Niwas

Abstract:
The present study was carried out on eight cattle and buffaloes had tumourous growth of different origin in oral cavity. Osteolysis, teeth displacement, calcification and soft tissue changes were found in radiographic examination. Histopathological examination revealed that all oral tumours were benign in nature. Vincristine sulphate @ 0.75mg/m2 body surface area intravenously at weekly interval for 4 to 6 times and anthiomaline @ 15-20 ml total dose by deep intramuscular injection six times on alternate days were administered. Out of eight animals, three animals showed recovery, four animal’s showed no or partial recovery while one animal died during the course of chemotherapeutic treatment. Inappetance to anorexia condition was common in all the animals. Results showed that vincristine sulphate with anthiomaline may give promising result in small size tumourous growth but large tumourous growth should be debulked by surgery before chemotherapy.