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Vol. 8, Issue 6 (2019)

Impact of body mass index and lipid profile among hypertensive patients including Pharmacoeconomics analysis: An Indian study

Author(s):
Irfana Sihabudeen, S Suwitha, Jency T James, S Parimalakrishnan and R Umarani
Abstract:
Objective: To find the prevalence of obesity and hyperlipidemia among hypertension patients and to analyze the prescription pattern and to study the cost analysis of antihypertensive therapy.
Methods: It was a Prospective observational cohort study done over a period of six months (Nov 2017 to April 2018) in a tertiary care teaching hospital in Chidambaram, Tamil Nadu. The patient demographics, BP, BMI, Lipid data were collected & recorded into data collection forms including patient’s prescription
Key findings: Total of 70 subjects was enrolled in the study. The age distribution of study shows maximum number of patients being in 70-80 years (33%). Majority of hypertensive subjects come under stage II hypertension (74%) and are considered to be obese (42%).70-80 year’s age group are having the highest average mean for BP which is 166.52 ± 29.17/93.91 ± 9.88 mmHg. The highest average BP (166.55 ± 28.44/96.55 ± 13.69 mmHg) was observed in obese patients. Furosemide (28%), Amlodipine (28%), Enalapril (28%) was most frequently prescribed drugs in monotherapy. Furosemide with Enalapril (36%) was most frequently prescribed drugs in double therapy. Furosemide with Enalapril with Amlodipine (45.40%) was most frequently prescribed drugs in triple therapy. Quadruple drug therapy was prescribed in accelerated hypertension cases.
Conclusion: The present study shows that blood pressure tends to increase as the age increases. Higher prevalence of BP was seen in obese patients. Hyperlipidemia was tending to be higher in Hypertensive crisis stage with increased BP. Mono therapy (45%) was highly preferred than combination therapies. Diuretics are more economical than ACE inhibitors, CCB and ARB. Prescription trend showed diuretics as first line treatment followed by ACE inhibitors, CCB and ARB which complies with AHA/ACC guidelines.
Pages: 1241-1244  |  357 Views  39 Downloads


The Pharma Innovation Journal
How to cite this article:
Irfana Sihabudeen, S Suwitha, Jency T James, S Parimalakrishnan, R Umarani. Impact of body mass index and lipid profile among hypertensive patients including Pharmacoeconomics analysis: An Indian study. Pharma Innovation 2019;8(6):1241-1244.

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