Toll Free Helpline (India): 1800 1234 070

Rest of World: +91-9810852116

Free Publication Certificate

Vol. 8, Issue 6 (2019)

Dosing pattern of insulin in diabetic foot ulcer patients

Author(s):
B Sarah Fazeeha, P Nivetha, Albin Eldhose, Dr. G Veeramani and Dr. J Kabalimurthy
Abstract:
Background: Among the Diabetic patients, 15% develop a foot ulcer and 12-24% of patients with diabetic foot ulcer require amputation. We compared the effectiveness of various dosing pattern of insulin statistically and planned to observe wound healing by proper glycemic control.
Methods: We compared the effectiveness of sliding and fixed scale dosing pattern of insulin and observed the wound healing by proper glycemic control. Total 50 subjects were recruited with Grade 3, 4 and 5 Diabetic foot ulcer (Wagner’s classification) between 40 and 70 years of age who underwent surgery for management of Foot ulcer. The study was conducted in Tertiary care teaching hospital in Chidambaram. The study period was 6 month and it was a prospective observational study. The blood glucose level (Fasting, Random and Post prandial) of subjects were monitored on daily basis and observed.
Results: The study reports suggested that the major risk factors for Diabetic Foot Ulcer were Poor glycemic control, Male gender, left foot, Ulcer of size more than 2cm, Infection. The Statistical analysis was done using SPSS software by applying Chi-square test and Mann Whitney test. The results showed that there is no statistically significant difference between sliding and fixed scale dosing of Insulin and both methods are reliable in maintaining glycemic control.
Conclusion: Our study show that poor glycemic control is one of the major risk factor leading to chronic wound and thus proper glycemic control must be ensured by adjusting Insulin dose according to patients’ Blood glucose level.
Pages: 1196-1199  |  308 Views  61 Downloads


The Pharma Innovation Journal
How to cite this article:
B Sarah Fazeeha, P Nivetha, Albin Eldhose, Dr. G Veeramani, Dr. J Kabalimurthy. Dosing pattern of insulin in diabetic foot ulcer patients. Pharma Innovation 2019;8(6):1196-1199.

Call for book chapter