Vol. 8, Issue 6 (2019)

Author(s):
Mohammed Salim KT, Dr. RT Saravanakumar and Dr. Dilip C

Abstract:
Hypertension is a lifestyle disease affecting majority of population around the world. The prolonged elevation in blood pressure can damage the nephrons and subsequently lead to chronic renal failure. According to Joint National Committee in its 8th revision suggest Angiotensing receptor blockers or Angiotensin converting enzyme inhibitor as the first line drug, being a regulator of blood flow has shown favorable impact for a patient with hypertensive CKD. However, they may also produce few adverse drug reaction i.e. hyperkalemia, hypotension, intermittent claudication which needs medical attention. Acute renal failure is an ADR that has been reported by Indian Pharmacopoiea Commission. Being a drug that is supreme among all other antihypertensive agents which is safe in CKD, they can also cause renal damage. Hence, the data regarding the prescription, adherence and efficacy need to be analyzed.