Vol. 8, Issue 6 (2019)

Methods: Terminalia paniculataroots were shade dried, powdered, and extracted by Soxhlet extraction procedure using ethanol. Standard procedures were used for preliminary phytochemical studies of the ethanolic extract. Staphylococcus aureus MTCC 96, Bacillus subtilis MTCC 441, Escherichia coli MTCC 443 and Pseudomonas aerugenosa MTCC 424 were chosen for antibacterial activities. Adult Indian earthworms Pheritima posthuma was used for anthelmintic activity.

Results: The results of antimicrobial susceptibility reveals ethanolic extract has promising antibacterial activity against gram-negative bacteria (E. coli and P. aerugenosa) as compared to gram-positive bacteria (S. aureus and B. subtilis). The ethanolic extract of Terminalia paniculata root revealed significant anthelmintic activity in a dose-dependent manner.

Conclusion: An ethanolic extract of Terminalia paniculata root possesses antimicrobial and anthelmintic activities.