Vol. 8, Issue 6 (2019)

Author(s):
Shamim and Saad Ahmed

Abstract:
Kunjad (Sesamum indicum) is a drug of herbal origin, belonging to the family pedaliaceae. Kunjad is one of the world’s important oil crops. While sesame seeds have been grown in tropical regions throughout the world since prehistoric times, traditional myths hold that their origins go back even further. According to Assyrian legend, when the Gods met to create the world, they drank wine made from sesame seeds. These seeds were thought to have first originated in India and were mentioned in early Hindu legends. In these legends, tales are told in which sesame seeds represent a symbol of immortality. Sesame seeds also contain two unique substances: sesamin and sesamolin known to have a cholesterol lowering effect in humans and to prevent high blood pressure. Both of these were also reported to increase the hepatic mitochondrial and the peroxisomal fatty acid oxidation rate in experimental animals. Cephalin, a phospholipid from sesame seed has been reported to possess hemostatic activity. The oil has wide medical and pharmaceutical applications. In this paper, an effort has been made to compile the phytochemical studies, pharmacological actions, therapeutic uses and pharmacological studies of Kunjad (Sesamum indicum).