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Vol. 8, Issue 6 (2019)

Synthesis, characterization and antimicrobial activity of boron, silicon and selenium substituted quinoxaline derivatives

Author(s):
Shaik Mahaboob Basha, Paala Krishna, Shaik Thaslim Basha, Chintha Venkataramaiah, Suban Syed Shafi and Chamarthi Naga Raju
Abstract:
A series of new quinoxaline derivatives was synthesized by reacting 2, 3-dichloro quionoxaline with various boronic acids, silicic acid and selenous acid in mild, efficient and convenient method with good yields in less time. All the newly synthesized compounds were characterized by IR, NMR (1H, 13C & 11B) and mass spectroscopy and also screened for their antimicrobial activity. Among the title compounds, 4-fluoro phenyl, 2,4-difluoro phenyl and 4-chloro phenyl groups substituted compounds at boron have showed potent antimicrobial activity when compared to the standard drugs.
Pages: 627-632  |  339 Views  108 Downloads


The Pharma Innovation Journal
How to cite this article:
Shaik Mahaboob Basha, Paala Krishna, Shaik Thaslim Basha, Chintha Venkataramaiah, Suban Syed Shafi, Chamarthi Naga Raju. Synthesis, characterization and antimicrobial activity of boron, silicon and selenium substituted quinoxaline derivatives. Pharma Innovation 2019;8(6):627-632.

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