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Vol. 8, Issue 6 (2019)

Effects of non enzymatic antioxidants on serum total proteins and its fractions in Magra rams in arid region of Rajasthan

Author(s):
Amit Kumar, Jitendra Singh Mehta, Govind Narayan Purohit, Ashok Kumar and Harvindra Kumar Narula
Abstract:
The objective of this study was to determine the effect of combination of vitamin E with selenium (Se) and vitamin C injections on serum total protein and its fractions in Magra rams. Twenty one Magra rams were randomly divided in three groups. The 1st group (n=7) was administered injection of normal saline (without antioxidant administration) 1ml SC once in a week as a placebo and was considered as a control (C). The rams of group 2nd (n=7) were given injections of selenium and vitamin E (1.5 mg sodium selenite and tocopherol 50mg/ml) 1ml SC per animal once in a week and considered as group VES. The rams of group 3rd (n=7) were given vitamin C (250mg sodium ascorbate/ml), 8 ml SC per animal on alternate days and considered as group VC. All the rams received the treatments for 45 days. Blood was collected twice in a week one month post-treatment for 5 consecutive weeks and serum was analyzed for serum total proteins and its fractions like albumin and globulin. Statistical analysis revealed significant (P<0.05) increase in concentration of serum total protein, albumin and globulin whereas A/G ratio remained unaffected by the treatment. The results of this experiment confirm a clear positive effect of parenteral administration of vitamin E combined with Se and vitamin C on serum total proteins and its fractions in rams.
Pages: 542-547  |  358 Views  55 Downloads


The Pharma Innovation Journal
How to cite this article:
Amit Kumar, Jitendra Singh Mehta, Govind Narayan Purohit, Ashok Kumar, Harvindra Kumar Narula. Effects of non enzymatic antioxidants on serum total proteins and its fractions in Magra rams in arid region of Rajasthan. Pharma Innovation 2019;8(6):542-547.

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