Vol. 8, Issue 6 (2019)

Author(s):
Neeraj Kumar Tyagi and Sunita Mishra

Abstract:
‘Nutrigenomics’ is one of the lively scientific advancement influencing mankind around the world. Food or more precisely 'nutrition' has the major impact in defining the cause response interaction between nutrient (diet) and human health. In addition to substantial understanding of nutrition human health interaction, bases of 'nutrigenomic' development foster on advent in transcriptomics, genomics, proteomics and metabolomics as well as insight into food as health supplement. Interaction of selected nutrient with associated genes in specific organ or tissue necessary to comprehend that how individual's genetic makeup (DNA transcribed into mRNA and then to proteins) respond to particular nutrient. It provided new opportunities to incorporate natural bioactive compounds into food for specific group of people with similar genotype. It covers the general overview of nutrigenomics, and the role of SNP in gene alteration, diet supplementation and public awareness. It is understood that with the increasing changes in the food habits and life styles, people are becoming more prone to diet related disorders. Therefore there is an urgent need to boost more research in this field to help people in understanding the relationship between diet and health with the development of product, and to ensure that everyone benefits from the genomic product revolution, various aspects of R&D in nutrigenomics are reviewed to ascertain its impact on human health, especially with lifestyle related diseases.