Vol. 8, Issue 5 (2019)

Author(s):
Amarjit Salunke, Dr. Neeraj Upamanyu, Arun Kumar Pandey and Pawan Kumar Rawat

Abstract:
Recent advances in nanotechnology paved path for design of new biomaterials based on nanoscale with many potential applications in the field of nanomedicine. Effective drug delivery at a targeted site had given the possibility to perform the precise function to control the release rates and have a better compliance on the health care system but the chemistry possessing complex form had made conditions complicated. But the invention of nanosponges has given a significant approach toward solving this problem. Nanosponges play an important role in targeting drug delivery in a controlled manner. A wide variety of drugs, both the lipophilic as well as hydrophilic can be loaded into nanosponge for targeting drug delivery and ultimately improve solubility and bioavailability of the same drug. Nanosponge can circulate around the whole body until they interact with the specific target site and stick on the surface and begin to release the drug in a controlled manner. This review attempts to elaborate the interesting features of nanosponges, recent updates of nanosponges in drug delivery and formulation development and evaluation of nanosponges for colon targeting.