Vol. 8, Issue 5 (2019)

Author(s):
K Tamilselvi, SP Anand and A Doss

Abstract:
The inhibitory properties of ethanol extract of Gardenia latifolia on glycosylation formation, was investigated in haemoglobin using Gallic acid as Standard. The periodic glycosylation of haemoglobin at varying concentration of glucose shows a decrease in haemoglobin concentration indicating the glycosylation of haemoglobin. While the subsequent administration of G. latifolia ethanol leaf extract inhibit haemoglobin glycosylation, where a concentration of 20 mg/ml of the extract gave a significant inhibition by yielding haemoglobin concentration of 1.324 mg/ml for test extract as against 1.18 mg/ml for the standard. The present study suggests that the crude ethanol extract inhibits the binding of glucose to hemoglobin, since at higher concentration of glucose the concentration was found to be high.