Vol. 8, Issue 5 (2019)

Author(s):
Sujesh M and Dr. Jyoti Harindran

Abstract:
Plants have been an important source of medicine since the beginning of human civilization and it still continues as one of the major source of drugs in modern as well as traditional medicine throughout the world. Despite the major advances in the modern medicine, the development of new drug from natural products is still considered important. Cyclea peltata of Menispermaceae family is commonly known as “Patha” and is herb which in mentioned in all ancient scriptures of Ayurveda. The great sage Charaka has categorized patha as “Sadhaniya”-means a healing herb. The roots have great medicinal value and are used both internally and externally. Externally it is used to treat infected wounds, sinuses, skin diseases and pruritus. Internally it is used as an anti-inflammatory, gastro-protective, anti-oxidant, immuno-modulatory, antiseptic etc. The present study deals with the qualitative and quantitative phytochemical analysis and GC-MS profiling of the ethyl acetate (CPEA) and petroleum ether extract (CPPE) of the root of Cyclea peltata. Phytochemical analysis shows the presence alkaloids, steroid, terpenoid, tannins in ethyl acetate extract (CPEA) and alkaloid and saponins in pet. ether extract (CPPE). The GC-MS chromatogram shows the presence of hexadecanoic acid, ethyl-9-octadecenoate for ethyl acetate extract (CPEA) and n-decanoic acid and hexadecanoic acid, cis-9-hexadecinal etc. for pet. ether extract (CPPE).