Toll Free Helpline (India): 1800 1234 070

Rest of World: +91-9810852116

Free Publication Certificate

Vol. 8, Issue 4 (2019)

Phytochemical and GC-HRMS analysis of active compounds of methanol extract of whole plant of Basella alba and their in vitro antioxidant activities

Author(s):
Mangesh S Hogale, Bibu JK and Usha PTA
Abstract:
Herbal medicines are getting more attention as conventional therapies showing resistance and other side effects. The plant Basella Alba is a leaf vegetable and traditionally used for different medicinal purpose. We investigated methanol extract of whole plant of Basella alba (MBA) for the presence of phytochemicals and antioxidant potential by in vitro methods. On phytochemical analysis, flavonoids, cardiac glycosides, phenols, saponins and diterpenes were detected. GC-HRMS analysis indicated the presence of the compounds belonging to class of pyrans, phytol, flavonoids, phenols, glycerides, esters, fatty acids, palmitic acid, diterpens and sterols. MBA showed significant (p < 0.05) concentration dependant DPPH, superoxide and nitric oxide free radical scavenging activity as well as total antioxidant activity. The half maximum inhibitory concentrations (IC50) obtained for DPPH, superoxide and nitric oxide free radical scavenging assays were 22.51 ± 7.81, 105.54 ± 8.53 and 43.123 ± 7.36 μg/mL respectively. Also significant (p < 0.05) increase in absorbance with increase in concentrations was observed during total antioxidant assay. Therefore, the present study designated a dose dependent antioxidant potential of methanol extract of whole plant of B. alba.
Pages: 893-899  |  538 Views  147 Downloads


The Pharma Innovation Journal
How to cite this article:
Mangesh S Hogale, Bibu JK, Usha PTA. Phytochemical and GC-HRMS analysis of active compounds of methanol extract of whole plant of <em>Basella alba </em>and their <em>in vitro </em>antioxidant activities. Pharma Innovation 2019;8(4):893-899.

Call for book chapter