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Vol. 8, Issue 4 (2019)

Multidrug resistance and ESBL profile of Salmonella serovars isolated from poultry birds and foods of animal origin

Author(s):
Y Suresh, CH Bindu Kiranmayi, T Srinivasa Rao, M Srivani, N Subhashini, G Chaitanya, B Swathi Vimala and B Suresh
Abstract:
Salmonella is a foodborne pathogen having a worldwide public health concern. The present study was undertaken to study antibogram profiles of multidrug resistant Salmonella isolates and detection of β-lactamase (ESBL-Extended Spectrum β-Lactamases) activity by both phenotypic and genotypic methods. Out of 21 Salmonella spp. isolated from different sources, antibiogram revealed 100% susceptibility to co-trimoxazole and polymyxin–B, intermediate resistance against ampicillin (28.57%), cefotaxime (19.04%), gentamycin (14.28%), amikacin (9.52%), ceftriaxone (9.52%), ciprofloxacin (9.52%), tetracycline (4.76%) and streptomycin (4.76%) while, higher resistance was observed towards amikacin (61.90%) followed by ampicillin (52.30%), tetracycline (38.09%), ceftriaxone (33.33%), gentamicin, sulfamethoxazole, cefpotaxime and nalidixic acid (28.57% each), ciprofloxacin (23.80%), doxycycline hydrochloride and chloramphenicol (19.04% each) and streptomycin (9.52%). Of the 21 Salmonella isolates, 15 isolates were found resistant to β-lactam antibiotics like ceftriaxone (33.33%), cefotaxime (28.57%), aztreonam (23.80%) and ceftazidime (23.80%). β-lactamase genes were detected in a total of 11 isolates (11/21, 52.38%) where blaTEM being the predominant gene detected (9/11, 81.18%), followed by blaCTX-M group-2 (2/11, 18.18%), blaOXA (1/11, 9.09%) and blaCTX-M group-9 (1/11, 9.09%) and no single isolate showed blaCTX-M group-1 and blaSHV genes.
Pages: 277-282  |  256 Views  20 Downloads
How to cite this article:
Y Suresh, CH Bindu Kiranmayi, T Srinivasa Rao, M Srivani, N Subhashini, G Chaitanya, B Swathi Vimala, B Suresh. Multidrug resistance and ESBL profile of <em>Salmonella </em>serovars isolated from poultry birds and foods of animal origin. Pharma Innovation 2019;8(4):277-282.
The Pharma Innovation Journal