Vol. 8, Issue 4 (2019)

Author(s):
Satyendra Kumar and Purshotam

Abstract:
Pharmaceutical nanotechnology has emerged as a revolutionary approach in drug delivery systems, offering precise targeting, enhanced efficacy, and reduced side effects. This paper explores the diverse applications of pharmaceutical nanotechnology in drug delivery, encompassing various nano-sized carriers such as liposomes, polymeric nanoparticles, dendrimers, and micelles. Through meticulous literature review and analysis, we delve into the mechanisms underlying nanoparticle-mediated drug delivery, highlighting the significance of size, surface properties, and formulation techniques. Furthermore, this paper elucidates the role of pharmaceutical nanotechnology in overcoming biological barriers, including the blood-brain barrier and the mucosal barrier, thereby facilitating the delivery of therapeutics to previously inaccessible sites. Additionally, we discuss recent advancements in the field, including stimuli-responsive nanocarriers and targeted delivery strategies, paving the way for personalized and precision medicine. Overall, this comprehensive review underscores the transformative potential of pharmaceutical nanotechnology in optimizing drug delivery and advancing therapeutic outcomes.