Vol. 8, Issue 2 (2019)

Author(s):
Mishra Gauridutt, Pandya DH, Harisha CR and Shukla VJ

Abstract:
Background: Simhanada Guggulu has Vata-Kapha Shamaka, Deepana, Pachana, Shulaghna properties, it is drug of choice of Amavata (Rheumatoid arthritis). A lot of work has been carried out on Simhanada Guggulu, this study will definitely strengthen the previous one. Aims: To evaluate Pharmacognostical and physico-chemical characters of Simhanada Guggulu. Materials & Methods: Prepared drug was collected from pharmacy I.P.G.T. & R.A. and authenticated in respective Laboratory of I.P.G.T. & R.A., G.A.U., Jamnagar. Standard procedures were followed to undertake the Pharmacognostical and physico-chemical analysis. Results: The Pharmacognostical results of Simhanada Guggulu showed Trichoma of Bibhitaki, Starch grain of Haritaki, Fibers of Amalaki, Silica deposition of Amalaki etc., without staining. Tannin content of Haritaki and Tannin content of Bibhitaki after staining with (Phloroglucinol & Con. HCL). Physicochemical analysis of Simhanada Guggulu revealed weight variation 18.53%, Hardness 3.0 kg/cm², Disintrigation time ˃ 1 hr. etc., In HPTLC, Simhanada Guggulu revealed 9 spots at 254 nm and 4 spots at 366 nm. Discussion: Pharmacognostical study helps in exact authentication of ingredients present in formulation through its organoleptic characters like taste, odor, color and touch along with microscopical characters and physico-chemical parameters. The presence of all contents of raw drugs in the final product shows the genuinity of the final product. All the pharmaceutical parameters analyzed showed values permissible for the Vati. Conclusion: As there are a lot of study on the Simhanada Guggulu, The findings of the study will definitely strengthen the previous one.