Vol. 8, Issue 2 (2019)

Modulation of immune functions by using medicinal plants and their products as a possible therapeutic measure has become fundamental principle of therapeutic approach. Plants and minerals have been used since ancient times for the treatment of many ailments and diseases. It is now being recognized that immunomodulation of immune response could provide an alternative to conventional chemotherapy for a variety of disease conditions, especially when host's defense mechanism has to be activated under the conditions of impaired immune responsiveness or when a selective immunosuppression has to be induced in situation like autoimmune disorders and organ transplantation.

In the present research work, immunomodulatory activities of Putranjiva roxburghii Wall. is evaluated by studying their protective effects against leucopenia/ neutropenia produced by a single dose of cyclophosphamide on Swiss albino mice. (In vivo study) and the results are compared with that of the known immunomodulators, Tinospora cordifolia Miers. (Rasayana plant) and lithium carbonate (Synthetic drug).