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Vol. 8, Issue 2 (2019)

Analysis of aminoglycoside residues in milk by high performance liquid chromatography

Author(s):
Sneh Lata Chauhan, SR Garg, Priyanka and Vijay J Jadhav
Abstract:
In the present study, High Performance Liquid Chromatography with Florescence detector (HPLC-FL) was standardized and validated for the detection and quantitation of aminoglycoside residues in milk. The validation studies showed that linearity (R2>0.99), accuracy (70-110%) and precision (<10%) were within accepted range with good specificity. Aminoglycoside residues found to be positive in 15 samples out of 100 samples. Comparison of antimicrobial concentration in each positive sample of milk was done with international MRLs. The risk assessment based on per capita availability of milk in Haryana and India by calculating hazard quotient for each analyte under study revealed no risk due to dietary exposure of aminoglycoside residues through milk.
Pages: 06-09  |  1227 Views  166 Downloads


The Pharma Innovation Journal
How to cite this article:
Sneh Lata Chauhan, SR Garg, Priyanka, Vijay J Jadhav. Analysis of aminoglycoside residues in milk by high performance liquid chromatography. Pharma Innovation 2019;8(2):06-09.

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