Vol. 8, Issue 12 (2019)
Evaluation of the antioxidant activity of the aqueous and methanolic extracts of Tetrapleura tetraptera (Schum. & Thonn.) Taub., 1891, (Mimosaceae) Barks, in vitro
Mawa Traore, Doumbia Idrissa, Yeo Sounta Oumar, Yapi Houphouet Felix, N Guessan Jean David and Djaman Allico Joseph
This study aimed to evaluate the antioxidant activity of aqueous and methanolic extracts of of Tetrapleura tetraptera barks. It’s a food plant that is also used by people in western Côte d'Ivoire, to treat various ailments. The quantitative estimate of the total phenolic contents of the aqueous extract by the colorimetric method showed that the aqueous extract (E. Aec) contains 78.66 ± 0.12 mg GAE/g of extracts while the methanolic extract (E. Mec) have 464.66 ± 0.22 mg GAE/g of extracts. As for total flavonoid, the quantity determined for the aqueous extract (E. Aec) is 17.33 ± 0.97 mg QE/g when the methanolic extract (E. Mec) gave 147.33 ± 0.45 mg QE/g of extracts. The evaluation of the antioxidant activity of extracts was carried out according to two methods: the free radical scavenging by the DPPH and the measurement of the reducing power (FRAP). The results obtained indicate that the methanolic extract contains more polyphenolic Compounds than the aqueous extract. The methanolic extract (E. Aec) antioxidant properties (E. Mec, IC50 = 02.57 ± 0.16 mg/mL) are also greater than those of the aqueous extract (E. Aec, IC50 = 07.50 ± 0.60 mg/mL). This antioxidant activity which remains close to that of vitamin C (01,25 ± 0.02) could represent an additional asset in the management of pathologies linked to oxidative stress.
How to cite this article:
Mawa Traore, Doumbia Idrissa, Yeo Sounta Oumar, Yapi Houphouet Felix, N Guessan Jean David, Djaman Allico Joseph. Evaluation of the antioxidant activity of the aqueous and methanolic extracts of <em>Tetrapleura tetraptera</em> (Schum. & Thonn.) Taub., 1891, (Mimosaceae) Barks, <em>in vitro</em>. Pharma Innovation 2019;8(12):49-53.