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Vol. 8, Issue 1 (2019)

Silver nanoparticles: A promising alternative approach to combat bacterial infections

Author(s):
Valli S, Deepa Jeyakumari V and Vimal M
Abstract:
The field of nanotechnology is the most active areas of research in modern material science. The synthesis of Nano biomaterials using biological processes is very fast, environment friendly and non-toxic. In the present study silver nanoparticles were synthesized using Acremonium species isolated from spoiled vegetables. They were characterized by UV, SEM, XRD and EDX. The silver nanoparticle synthesized using Acremonium species was tested for antibacterial activity against pathogenic microbes Bacillus subtilis, Klebshiella pneumoniae, Salmonella typhi, staphylococcus aureus, Shigella boydii, Proteus vulgaris, Pseudomonas aurogenosa and Escherichia coli. The AgNPs showed highest antibacterial activity against Klebsiella pneumonia followed by E. coli, S. typhi, Shigella sp., Proteus mirabilis, S. aureus and B. subtilis. It was found that Gram negative bacteria were inhibited to greater extent by silver nanoparticles than Gram positive. The combined use of AgNPs with other antimicrobial agents reduce problem of toxicity and avoid the potential for development of resistance and strongly enhance the microbicidal effect.
Pages: 522-527  |  168 Views  5 Downloads
How to cite this article:
Valli S, Deepa Jeyakumari V, Vimal M. Silver nanoparticles: A promising alternative approach to combat bacterial infections. Pharma Innovation 2019;8(1):522-527.
The Pharma Innovation Journal