Vol. 8, Issue 1 (2019)

Author(s):
K Balamurugan, Naresh Kshirasagar and P Govardhan

Abstract:
Microsponges are particulate drug delivery system composed of porous nature. They are small tiny sponges like spherical particles with large porous surface moreover they may heighten the stability by modifying the drug release pattern with reduced side effects. Microsponges Delivery System (MDS) can suspend or entrapped a wide variety of substance which act as carrier and can then be incorporated into a formulated product such as a gel creams or powder. The main aim of the formulation is to achieve desired concentration of the drug in the blood. Microsponges of its porous nature that are mostly used for topical application but recently been used for oral administration. Microsponges are design to deliver a pharmaceutical active ingredient in efficiently without adverse effects in sustained manner, one of the best feature of Microsponges is it has self-sterilizing property, numerous study has confirmed that Microsponges are non-irritation, non-mutagenic, non-allergic and nontoxic.