Biopharmaceutics: Drug absorption and bioavailability
Author(s): Smriti Malviya
Abstract: This research paper delves into the intricate mechanisms governing biopharmaceutics, particularly focusing on drug absorption and bioavailability. Biopharmaceutics plays a pivotal role in determining the efficacy and safety of pharmaceutical compounds by elucidating the processes involved in their absorption, distribution, metabolism, and excretion within the body. Through a comprehensive review of current literature and methodologies, this study examines various factors influencing drug absorption, including physicochemical properties of drugs, formulation characteristics, and physiological factors within the gastrointestinal tract. Moreover, it investigates the significance of bioavailability, which reflects the fraction of an administered dose of drug that reaches the systemic circulation in an unchanged form. Understanding the complexities of biopharmaceutics is essential for optimizing drug delivery systems and enhancing therapeutic outcomes. This paper underscores the importance of continued research in biopharmaceutics to advance drug development and improve patient care.