Vol. 7, Issue 8 (2018)

Author(s):
Havryltsiv ST

Abstract:
Histomorphometry of bone tissue is still an important method of an objective evaluation of mechanisms of remodeling at cellular and tissue levels, which allows to reliably study the morphological manifestations of osteoporosis. We set the goal to study the microarchitecture of jaw bones with their histomorphometric study in patients with radicular cysts on the background of osteoporosis and without violations of mineral metabolism. Histological materials for histomorphometric study were obtained during radicular bone removal (cystectomy). After semi-automatic image transfer of histoparticles into black and white (binary masks), using the ImageJ software, the following parameters were measured: trabecular space, intertrabucular space, the area of ​​the cross-section between the trabecular space (μm²) and the histomorphometric coefficient of bone density. In response to the pathological effects of radicular cysts, irrespective of their size, an adaptive-compensatory reconstruction of the jaw bones occurs that morphologically manifests as a sealing of their trabecular structure, and the decrease of the intertrabecular space. The state of mineral metabolism in patients affects the osteo-regenerative potential in jaw bones.