Phytochemical screening and anti-inflammatory activity of Moringa oleifera pods-an in vivo design
Devi Prasuna Kalluri, Mohammed Sayeed, Vasudha Bakshi and Narender Boggula
Back ground: The practice of herbal medicine dates back to the very earliest period of known human history. There are evidences that herbs have been used in the treatment of diseases and for revitalizing the body system though most of the plants do not possess effective documentation supporting their activity. Objective: In the present research the methanolic extract of Moringa oleifera pods was evaluated for its phytochemical constituents and physicochemical analysis along with its anti-inflammatory activity. Method: The pharmacognostic study was performed by following standard protocols and in vivo anti-inflammatory activity was evaluated by carrageenan induced oedema model with the help of Zeitlin’s constant loaded lever apparatus. Results: The physicochemical analysis showed the total ash value, water soluble extractive value and acid insoluble ash value was 9.0%w/w, 2.0%w/w, 1.5%w/w respectively. The phytochemical analysis revealed the presence of alkaloids, carbohydrates, phenols, tannins, flavonoids, saponins and glycosides. The anti-inflammatory activity showed at the doses of 200 and 400 mg/kg b.w and Indomethacin at 10mg/kg produced dose dependent significant reduction in carrageenan induced rat maximal paw oedema. Conclusion: The methanolic extract of Moringa oleifera pod has potential in terms of anti-inflammatory properties. These data’s would help in the development of pod profile for the plant, and can be used in herbal medicines as it has fewer side effects as compared to those synthetic drugs.
How to cite this article:
Devi Prasuna Kalluri, Mohammed Sayeed, Vasudha Bakshi, Narender Boggula. Phytochemical screening and anti-inflammatory activity of Moringa oleifera pods-an in vivo design. Pharma Innovation 2018;7(7):673-679.