Vol. 7, Issue 7 (2018)

Author(s):
S Meher, AR Gupta, HK Dalai, SM Nayak, P Samal, K Sethy, P Meher, MR Das and RC Patra

Abstract:
Canine pyoderma is a major skin disease of dog that may lead to increased risk of oxidative stress. The following study was carried out in 40 dogs out of which twenty were pyoderma affected takrn as Group 2 and twenty were healthy dogs (Group 1) treated as control. This study was done to estimate oxidative stress biomarkers (Lipid peroxidase, Super oxide dismutase, Catalase). Analysis of these erythrocytic oxidative stress indices revealed significantly high (p<0.05) Lipid peroxidase (LPO) value and significant low (p<0.05) Super oxide dismutase (SOD) and Catalase values at day 0 of experiment. Bacterial isolation and culture was done where Coagulase positive staphylococcus aureus species was isolated. In antibiotic sensitivity test azithromycin was found to be highest sensitive. After antibiotic therapy the altered oxidative stress indices are subsequently found to be normalised at day 30 of the experiment.