Post-operative wound infection: isolation, characterization and in vitro antibiotic susceptibility analysis
Pramila M, Meenakshisundaram M, Prabhusaran N, Lalithambigai J and Karthik P
There is a fast emergence and vivid spread of multi-drug resistant super bugs in the hospital environment. Now a days, the drastic increase in the post-surgical infections are found due to various intrinsic and extrinsic factors. This investigation provide some idea about the prevalence of aerobic bacterial pathogens responsible for the post-operative wound infections and non-healing of the surgery induced wounds. A total of 50 post-operative cases with various surgeries and days of stay were recruited therby 65 bacterial isolates were characterized. Out of them, Staphylococcus aureus dominated followed by Pseudomonas aeruginosa and Escherichia coli. In the polybacterial determination, the combination of Staphylococcus aureus, Escherichia coli and Proteus vulgaris observed with maximum numbers. By determining the in vitro antibiogram, Staphylococcus aureus showed maximum resistant towards penicillin, tetracycline and tigecycline whereas, Escherichia coli showed resistance towards all antibiotics. One each of the isolates of Pseudomonas aeruginosa and Proteus vulgaris showed resistance to all antibiotics. Among the two isolates of Klebsiella pneumoniae, cefoxitin, etrapenem and ceftriazone are not effective and showed resistance. From this study, it was concluded that the appropriate usage of the antibiotics reduce the evolution of superbugs thereby nosocomial infections and drug failure cases will be reduced.
How to cite this article:
Pramila M, Meenakshisundaram M, Prabhusaran N, Lalithambigai J, Karthik P. Post-operative wound infection: isolation, characterization and in vitro antibiotic susceptibility analysis. Pharma Innovation 2018;7(7):169-175.