Vol. 7, Issue 6 (2018)
Haemato-biochemical changes and therapeutic management of urinary tract infection in canines
B Roopali, M Roy and S Roy
The present study was carried out to investigate the haemato-biochemical changes, urine analysis and treatment of urinary tract infection in canines. Seven female and three male dogs between 8-10 years old were presented to TVCC, Veterinary College, Durg and Private Clinic, Bhillai (Chhattisgarh) with a history of inappropriate urination like dysuria, stranguria, haematuria, or pollakiuria were included in the study. Blood samples were collected from the study group animals for the estimation of various haemao-biochemical parameters. Haemoglobin, PCV, TEC and lymphocytes were significantly reduced in affected dogs when compared to the healthy control group indicative of severe anaemia. TLC and neutrophil count were significantly increased in the affected animals compared to the control group suggestive of bacterial infection. There was significant elevation of BUN and creatinine along with significant decrease in the total protein, albumin and globulin in the affected dogs as compared to the healthy control group. For urinalysis, urine samples were collected by cystocentesis. Microscopic examination of urine sediment revealed pus cells suggestive of pyuria. Urine culture revealed the major presence of E. coli organism followed by P. aerugenosa. Hence, the affected dogs were diagnosed for urinary tract infection of bacterial origin and treated accordingly. The dogs were administered with tab prulifloxacin @ 600 mg orally once a day for 5 days along with other supportive treatment. Haemato-biochemica parameters were estimated on 6th day post treatment and were within normal physiological limits. Urine culture was found negative to microorganisms and microscopic examination of urine sediment was negative to pus cells on 6th day of treatment suggestive of absence of urinary tract infection.
How to cite this article:
B Roopali, M Roy, S Roy. Haemato-biochemical changes and therapeutic management of urinary tract infection in canines. Pharma Innovation 2018;7(6):89-92.