Extra-intestinal manifestations of IBD involving musculo-skelatal system
Dr. Seema Mishra
Ulcerative colitis is an autoimmune disorder of unknown etiology. Although the large intestine is the major focus of autoimmunity, resulting in chronic diarrhea, that is actually a systemic disease, with numerous extraintestinal manifestations, such as articular involvement. The frequent association of a number of autoimmune diseases in the same patient has been described. However, the coexistence of ulcerative colitis and rheumatoid arthritis is rare. Extraintestinal manifestations (EIMs) of inflammatory bowel disease (IBD) are common in both ulcerative colitis (UC) and Crohn's disease (CD). These manifestations can involve nearly any organ system—including the musculoskeletal, dermatologic, hepatopancreatobiliary, ocular, renal, and pulmonary systems—and can cause a significant challenge to physicians managing IBD patients. Most IBD patients with EIMs have colonic inflammation, although some patients develop EIMs prior to the onset of colonic symptoms. In this paper, we review the major EIMs of IBD and strategies for their management. Thus chronic patients of IBD were analysed for symptoms of Arthritis and a significant number of studied patients had found early –late symptoms of joint problems in this work.
How to cite this article:
Dr. Seema Mishra. Extra-intestinal manifestations of IBD involving musculo-skelatal system. Pharma Innovation 2018;7(5):21-25.