Therapeutic management of oxidative stress in cattle, naturally affected with bovine tropical theileriosis by vitamin e and selenium
SM Nayak, SK Senapati, P Samal, K Sethy, S Meher, P Swain, PR Sahoo and MR Das
Topical Theileriosis is a blood protozoan disease of cattle which not only causes high mortality among the animals but also impacts huge economic losses to the farmers due to reduced quality and quantity of milk yield and impaired reproductive performances. Oxidative stress and lipid peroxidation in erythrocytes of cattle infected with Theileria annulata causes increased erythrocyte fragility and membrane lysis. For the present study, 20 Theileria affected cattle were selected and divided into two groups 10 cattle each i.e. Group II (treated with Buparvaquone with Marbofloxacin) and Group III (treated with vitamin E and selenium along with Buparvaquone with Marbofloxacin). Another 10 healthy cattle were taken as the healthy control group (Group I). It was found that there was a significant increase (p<0.05) of LPO and a significant decrease in SOD, Catalase, Hb, TEC, PCV, TLC in the group II and Group III as compared to Group I at day 0 of study. It is also shown that the Group III animals revealed a rapid recovery from typical clinical signs, oxidative stress and from haemato-biochemical alterations, as compared to the Group II. This indicated that the administration of vitamin E and selenium along with Buparvaquone and Marbofloxacin in tropical Theileriosis potentiated the efficacy of the anti-theilerial drug by elevating the antioxidant level of the affected animal.
How to cite this article:
SM Nayak, SK Senapati, P Samal, K Sethy, S Meher, P Swain, PR Sahoo, MR Das. Therapeutic management of oxidative stress in cattle, naturally affected with bovine tropical theileriosis by vitamin e and selenium. Pharma Innovation 2018;7(4):1141-1145.