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Vol. 7, Issue 4 (2018)

Surgical approach for mammary tumor in canines: case report

Author(s):
Kolipaka Rajesh and J Shiva Jyothi
Abstract:
In Veterinary medicine, mammary tumors represent the most frequently diagnosed neoplasm in intact female dogs, and 50% of these are malignant. A study focusing on the incidence of canine mammary tumors found tumors in approximately 0.05% of females that were spayed before their first heat cycle. This figure increased to 8% or 26% when the animals were spayed after their first or second heat, respectively. However, if the animals were spayed later, the risk of developing malignant tumors (MN) was the same as for an intact bitch. Mammary tumors can vary in size from a few millimeters to over a few centimeters, and at least 50% of the cases present multiple masses mainly located at the caudal glands. Generally, in canine mammary tumors (CMT), especially in metastatic tumors, genes in charge of DNA repair show genetic instability with unknown causes. Nevertheless, it is believed that aberrant tumor cell division with damaged DNA replication, hypoxia, mutations accumulation and DNA repair genes, epigenetic modifications can contribute to this phenomenon. This article describes canine mammary surgical treatment as an approach to remove the benign tumor.
Pages: 247-248  |  1046 Views  83 Downloads


The Pharma Innovation Journal
How to cite this article:
Kolipaka Rajesh, J Shiva Jyothi. Surgical approach for mammary tumor in canines: case report. Pharma Innovation 2018;7(4):247-248.

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