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Vol. 7, Issue 4 (2018)

Foot-and-mouth disease and vaccination

Vishweshwar Kumar Ganji, Mallesh Pottabathula, Sampath Kontham and Pruthvi Raj Boga
Foot and mouth disease is an infectious and highly contagious viral disease of domestic and wild cloven-hoofed animals. Vaccination is a major means to control FMD in most endemic areas. Current FMD vaccines are typically produced by inactivation of cell culture virus with binary ethylenimine and formulated with oil adjuvant. This vaccine has a subset of limitations such as requirement for frequent booster doses, poor cellular response, improper inactivation of virus. The focus has been shifted for production of an alternative, more desirable vaccine formulations like live attenuated vaccines, live vectored vaccines, DNA vaccines, subunit vaccines, virus like particles etc., which are achieved through rDNA technology.
Pages: 01-03  |  1180 Views  86 Downloads

The Pharma Innovation Journal
How to cite this article:
Vishweshwar Kumar Ganji, Mallesh Pottabathula, Sampath Kontham, Pruthvi Raj Boga. Foot-and-mouth disease and vaccination. Pharma Innovation 2018;7(4):01-03.
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