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Vol. 7, Issue 3 (2018)

The role of the hemomicrocirculatory system in the pathogenesis of chronic inflammatory processes of the internal genital organs in women

Author(s):
NV Drohomyretska and NI Henyk
Abstract:
The objective of the research: To study the peculiarities of violations of the hemomicrocirculatory bed of the bulbar conjunctiva in women with isolated chronic inflammatory processes of the internal genital organs and against the background of varicose veins of the small pelvis before and after the treatment.
Material and methods: There were examined before and after the treatment 54 women with chronic inflammatory processes of the internal genital organs against the background of varicose veins of the small pelvis (group I); 46 women – with chronic inflammatory processes of the pelvic organs without varicose veins of the small pelvis (group II); 30 – practically healthy women (control group). The age of women was between 18 and 45 years old. All patients of the study groups received the treatment offered by us, which included a diosmin-containing phlebotropic medicine of 500 mg twice a day in a continuous mode and a 5-ml nitric oxide donator for 3 times daily per so for 14 days each month during six months. Bulbar microscopy was performed with the help of SHCHL-2B slit lamp. The results of microscopy were evaluated according to the system of V.S. Volkov et al. (1976). Morphometry of the micro-vessels of the conjunctiva of the eyeball was carried out using photographic negatives based on the increase of SHCHL-2B.
Results: It was determined that in both of the examined groups there was a violation of hemomicrocirculation, which was systemic. After the performed treatment, the positive dynamics of changes in the hemomicrocirculatory bed was noted, especially in the group of patients with chronic inflammatory processes of the pelvic organs without varicose veins of the small pelvis. In the group of patients with chronic inflammatory processes of internal genital organs, which developed against the background of varicose veins of the small pelvis, positive intravascular and extravascular changes were revealed. The shape and size of the micro-vessels changed slightly.
Conclusions
1. Violation of hemomicrocirculation is one of the main components of the pathogenesis of chronic inflammatory processes of internal genital organs, both against the background of varicose veins of the small pelvis and without varicose veins of the small pelvis.
2. Changes in hemomicrocirculation in chronic inflammatory processes of the internal genital organs against the background of varicose veins of the small pelvis and without varicose veins of the small pelvis are systemic in nature, as evidenced by the data of bulbar microscopy of the conjunctiva.
3. After the performed treatment offered by us, the improvement of hemomicrocirculation occurs, especially in the group of patients with chronic inflammatory processes of the internal genital organs without varicose veins of the small pelvis.
Pages: 169-172  |  460 Views  9 Downloads
How to cite this article:
NV Drohomyretska, NI Henyk. The role of the hemomicrocirculatory system in the pathogenesis of chronic inflammatory processes of the internal genital organs in women. Pharma Innovation 2018;7(3):169-172.
The Pharma Innovation Journal