Evaluation of combined effect of Azadirachta indica and Khaya senegalensis oils on common fastidious microorganisms
Author(s):
Falmata M Aliyu, Mohammed Kachallah, Yusuf Bulus, Fatima A Goje, S Amshi and Abdulqadir B Bababe
Abstract:
The profound use of Khaya senegalensis oil (K. S) and Azadirachta indica oil (A. I) in Northern Nigeria herbal medicine practice and the promising result outcome have marked these plants oils as those whose curative potentials may be harnessed in the manufacturing of useful drugs that can be viable alternatives to some of the present day antibiotics. The aim of this study was to evaluate the antimicrobial properties of Khaya senegalensis oil and Azadirachta indica oil. Both oils were obtained from Uba central market of Borno State and tested for antimicrobial activities using serial dilution and agar well dilution using Levofloxacin as the standard. The activity index of the oil was also determined. Result showed that A. indica oil demonstrated a lower activity than K. senegalensis oil on Klebsella pneumoniae, Staph aureus and E. coli. However, synergistic study showed that the extracts when combined give a higher antimicrobial activity than the crude extracts alone.
How to cite this article:
Falmata M Aliyu, Mohammed Kachallah, Yusuf Bulus, Fatima A Goje, S Amshi, Abdulqadir B Bababe. Evaluation of combined effect of Azadirachta indica and Khaya senegalensis oils on common fastidious microorganisms. Pharma Innovation 2018;7(2):183-186.