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Vol. 7, Issue 2 (2018)

In vitro screening of Ashwagandha root extracts for the maximum functional components

Author(s):
Ashok Kumar Yadav and Dinesh Chandra Rai
Abstract:
In the present study, the most effective solvent (among ethanol, water, methanol and acetone) for extracting the major antioxidant compounds especially polyphenolics from Ashwagandha root using various in vitro tests including 1, 1-diphenyl-2-picryl-hydrazil (DPPH) free radical scavenging, metal ion chelating, hydrogen peroxide scavenging, superoxide anion radical scavenging, and ferric thiocyanate reducing ability were identified. Ethanolic extract of Withania somnifera had significant (p<0.01) (DPPH) free radical scavenging (82%), metal ion chelating (78.88%), hydrogen peroxide scavenging (91.36%), superoxide anion radical scavenging (67.66%) and significant (p<0.05) ferric thiocyanate reducing activities. Therefore ethanol extract of Ashwagandha root have been found to have maximum functional components e.g. polyphenols and antioxidants.
Pages: 12-16  |  1816 Views  502 Downloads


The Pharma Innovation Journal
How to cite this article:
Ashok Kumar Yadav, Dinesh Chandra Rai. In vitro screening of Ashwagandha root extracts for the maximum functional components. Pharma Innovation 2018;7(2):12-16.

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