Vol. 7, Issue 12 (2018)
Chenopodium album ameliorates cyclophosphamide-induced hyperlipidemia in Sprague dawley rats
Manish Kumar Verma, AH Ahmad, Disha Pant, Naveen Kumar and PC Patwal
Hyperlipidemia is the common cause of cardiovascular diseases associated by increasing total cholesterol, Triglyceride, athrogenic index, LDL and decreasing level of HDL. Cyclophosphamide is an alkylating drug used for the treatment of different types of cancer. Chenopodium album is herbal medicinal plant found worldwide in early grain field. It contains phytochemical components such as alkaloid, flavonoids, saponins, mineral and essential oil. This study was aimed to determine lipid profiles of cyclophosphamide induced hyperlipidemic Sprague dawley rats which given the hydroethanolic extract of Chenopodium album. The result showed that giving of extract of Chenopodium album reduced the triglyceride, total cholesterol, LDL-Cholesterol levels, and increased of HDL-cholesterol levels significantly (P˂0.05) in rats.
How to cite this article:
Manish Kumar Verma, AH Ahmad, Disha Pant, Naveen Kumar, PC Patwal. <em>Chenopodium album</em> ameliorates cyclophosphamide-induced hyperlipidemia in Sprague dawley rats. Pharma Innovation 2018;7(12):423-426.