Toll Free Helpline (India): 1800 1234 070

Rest of World: +91-9810852116

NAAS RATING: 5.23, Impact Factor: RJIF 5.98 | Free Publication Certificate
updates
NAAS Rating: 5.23 new
Vol. 7, Issue 12 (2018)

Cytotoxicity of various extracts of Indigofera barberi Gamble

Author(s):
Srinivasan N
Abstract:
Indigofera barberi Gamble (Fabaceae) plant traditionally used to treat various skin diseases, renal disease and liver disease. Reported Phytochemicals are glycosides, steroids, tannins and Phenolic compounds and flavonoids. However, no studies have been investigated for cytotoxic effect. The present study carried out to investigate the cytotoxic effect of petroleum ether, chloroform and ethanolic extracts of this plant on the growth of the human liver hepatoma cell lines were examined by MTT assay. The IC50 value of petroleum ether, chloroform and ethanolic extracts of Indigofera barberi in HepG2 cell line found to be 150mg/mL, 100mg/mL and 75mg/mL respectively. Among the tested cell lines, ethanolic extract of was more selective cytotoxic against HepG2 cell line. The Compound IB-4, isolated by further subjected from ethanolic extracts and its IC50 value found to be 40mg/mL.
Pages: 349-351  |  199 Views  3 Downloads
How to cite this article:
Srinivasan N. Cytotoxicity of various extracts of<em> Indigofera barberi </em>Gamble. Pharma Innovation 2018;7(12):349-351.
The Pharma Innovation Journal