Vol. 7, Issue 12 (2018)

Author(s):
Caroline Daisy and B Ravindran Durai Nayagam

Abstract:
The chemistry of heterocyclic compounds was used to prepare 2-mercaptobenzimidazole and its derivatives for obtaining novel biologically active ingredients such as anthelmintic, anti-HIV, antifungal, antibacterial, CNS depressant, anti-inflammatory, and analgesic activities. In this present study, a derivative of 2-mercaptobenzimidazole has been prepared and characterized. FTIR, 1H NMR and 13C NMR have strongly supported the formation 2-((2,4,6-trimethylbenzyl)thio)-1H-benzo[d]imidazole and the synthetic route has been validated by comparing the results with theoretical FTIR, 1H NMR and 13C NMR characterization. The synthesised compound have very potential antimicrobial activity against Staphylococcus aureus bacterium and Aspergillus niger fungi.