Vol. 7, Issue 10 (2018)

Author(s):
Jayprakash S Suryawanshi and Shivaji P Gawade

Abstract:
In the present study an attempt was made to formulate and assess the nanoemulsion formulation of Lepidium sativum Linn. (Garden Cress) seed oil (LSNE). Lepidium sativum seed oil contains many chemical constituents chiefly unsaturated fatty acids, α-tocopherol and have several pharmacological properties like antibacterial, antifungal, antioxidant, anti-inflammatory, and the oil is also responsible for relieving the pain in joints and rheumatism. Nanoemulsion was prepared by using non-ionic surface-active agent Tween 80, Span 20 and water by Ultrasonication technique. The average droplet size of the optimized nanoemulsion was determined as 208 nm. Evaluation of the nanoemulsion included analysis of particle size, polydispersity index, zeta potential, Ph, viscosity, refractive index and physical stability. The developed Nano formulation was found to be stable at long term stability study.