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Vol. 7, Issue 10 (2018)

Development and evaluation of Lepidium sativum seed oil nanoemulsion

Author(s):
Jayprakash S Suryawanshi and Shivaji P Gawade
Abstract:
In the present study an attempt was made to formulate and assess the nanoemulsion formulation of Lepidium sativum Linn. (Garden Cress) seed oil (LSNE). Lepidium sativum seed oil contains many chemical constituents chiefly unsaturated fatty acids, α-tocopherol and have several pharmacological properties like antibacterial, antifungal, antioxidant, anti-inflammatory, and the oil is also responsible for relieving the pain in joints and rheumatism. Nanoemulsion was prepared by using non-ionic surface-active agent Tween 80, Span 20 and water by Ultrasonication technique. The average droplet size of the optimized nanoemulsion was determined as 208 nm. Evaluation of the nanoemulsion included analysis of particle size, polydispersity index, zeta potential, Ph, viscosity, refractive index and physical stability. The developed Nano formulation was found to be stable at long term stability study.
Pages: 414-418  |  496 Views  93 Downloads


The Pharma Innovation Journal
How to cite this article:
Jayprakash S Suryawanshi, Shivaji P Gawade. Development and evaluation of <em>Lepidium sativum</em> seed oil nanoemulsion. Pharma Innovation 2018;7(10):414-418.
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