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Vol. 7, Issue 10 (2018)

Anticancer activity of derivatives of 2-Mercaptobenzimidazole – Molecular docking approach

Author(s):
Caroline Daisy, B Ravindran Durai Nayagam and E Vadivel
Abstract:
Nowadays cancer threats everyone since it is growing with uncountable varieties. Researchers are in urge to find suitable antibodies to each case. Molecular docking is one of the best tool to carry this emergent job within short time. With the help of molecular docking theoretical approach, this present study carried by taking three derivatives of 2-mercaptobenzimidazole as anticancer dote. The molecular docking study of selected three compounds were performed by using Autodock vina against EGFR tyrosine kinase protein. The docking study revealed that synthesised compounds are potential anticancer drugs especially IMM3 shows best binding efficiencies.
Pages: 279-283  |  814 Views  136 Downloads


The Pharma Innovation Journal
How to cite this article:
Caroline Daisy, B Ravindran Durai Nayagam, E Vadivel. Anticancer activity of derivatives of 2-Mercaptobenzimidazole – Molecular docking approach. Pharma Innovation 2018;7(10):279-283.

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