Toll Free Helpline (India): 1800 1234 070

Rest of World: +91-9810852116

NAAS RATING: 5.23, Impact Factor: RJIF 5.98 | Free Publication Certificate
updates
NAAS Rating: 5.23 new
Vol. 7, Issue 1 (2018)

A comprehensive review on sustained release drug delivery systems

Author(s):
Pawan Jalwal, Balvinder Singh and Surender Singh
Abstract:
Among all drug delivery system, oral drug delivery is the most preferred route for administration of various drugs. Sustained release products provide advantage over conventional dosage form by optimising pharmacokinetic and pharmacodynamic properties of drug. The sustained release formulation provides important way to decrease the side effect of drug by preventing the fluctuation of the therapeutic concentration of the drug in the body. These dosage forms are available in extended release, targeted release, delayed release, prolonged action dosage form. Some factors like molecular size, diffusivity, pKa-ionization constant, release rate, dose and stability, duration of action, absorption window, therapeutic index, protein binding, and metabolism affect the design of sustained release formulation. This article contains various types, evaluation and factors affecting the design of sustained release formulation.
Pages: 349-352  |  527 Views  16 Downloads
How to cite this article:
Pawan Jalwal, Balvinder Singh, Surender Singh. A comprehensive review on sustained release drug delivery systems. Pharma Innovation 2018;7(1):349-352.
The Pharma Innovation Journal