Review on colon targeted drug delivery for inflammatory bowel disease
Nazneen Dewan, Dr. Abdul Baquee Ahmed and Dr. Deboprotim Dasgupta
The colon is a site where both local and systemic delivery of drugs can take place. Local delivery allows topical treatment of inflammatory bowel disease. However, treatment can be made effective if the drugs can be targeted directly into the colon, thereby reducing the systemic side effects. Targeted drug delivery system is the system in which the dosage form is modified to deliver the drug at the target region or at the disease region. This targeting of drug to the disease site lowers the requirement of higher doses of drug thus reducing the dosage frequency and cost of the drugs. Colonic drug delivery has gained increased importance not just for the delivery of the drugs for the treatment of local diseases associated with the colon like Crohn’s disease, ulcerative colitis, inflammatory bowel disease etc but also for the systemic delivery of proteins, therapeutic peptides, anti-asthmatic drugs, antihypertensive drugs and anti-diabetic agents.
How to cite this article:
Nazneen Dewan, Dr. Abdul Baquee Ahmed, Dr. Deboprotim Dasgupta. Review on colon targeted drug delivery for inflammatory bowel disease. Pharma Innovation 2018;7(1):98-103.