Haematological study in hexavalent chromium toxicity in female wistar rats and its progeny
Jeevana Latha M, Dr. Srikanth MK, Dr. Gopala Reddy A and Dr. Anudeep Reddy M
An experiment was conducted to study the haematological profile in 120 female wistar rats in chromium toxicity. Rats were provided with feed and water ad libitum. The duration of experiment was for four months. There were six groups where as group I was the control group. Group II was provided with potassium dichromate @ 500ppm in drinking water orally for three months along with the basal diet, group III was treated as Vitamin C control, group IV as Emblica officinalis control, group V and VI were protective and ameliorative groups. The haematological profile revealed a significant (p<0.05) reduction of haemoglobin (Hb), packed cell volume (PCV), total erythrocyte count (TEC) and total leukocyte count (TLC) in toxin group. Group V and VI recorded mild to moderate results indicating the protection offered by ameliorating agents used in the feed (Vitamin C @100 mg/kg body weight and Emblica officinalis@ 2%).
How to cite this article:
Jeevana Latha M, Dr. Srikanth MK, Dr. Gopala Reddy A, Dr. Anudeep Reddy M. Haematological study in hexavalent chromium toxicity in female wistar rats and its progeny. Pharma Innovation 2018;7(1):35-38.